Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30376090 | 0.92 | L3MBTL1 (0.77) | L3MBTL1ABCG2NPC1KDM4EMEN1 | |
| SCHEMBL19267888 | 0.92 | L3MBTL1 (0.77) | L3MBTL1ABCG2NPC1KDM4EMEN1 | |
| SCHEMBL1421600 | 0.89 | ABCG2 (0.67) | L3MBTL1ABCG2NPC1KDM4EMEN1 | |
| SCHEMBL4268322 | 0.89 | L3MBTL1 (1.00) | L3MBTL1ABCG2NPC1KDM4EMEN1 | |
| SCHEMBL738489 | 0.88 | MEN1 (0.71) | L3MBTL1ABCG2MEN1KMT2AALDH1A1 | |
| SCHEMBL8064295 | 0.88 | L3MBTL1 (0.71) | L3MBTL1ABCG2NPC1KDM4EMEN1 | |
| SCHEMBL8066758 | 0.87 | L3MBTL1 (0.72) | L3MBTL1ABCG2NPC1KDM4EMEN1 | |
| Chrysin Dimethyl Ether SCHEMBL29403280 | 0.86 | ABCG2 (1.00) | ABCG2NPC1KDM4EMEN1KMT2A | |
| Chrysin Dimethyl Ether SCHEMBL1676012 | 0.86 | ABCG2 (1.00) | ABCG2NPC1KDM4EMEN1KMT2A | |
| SCHEMBL31238392 | 0.85 | KDM4E (0.83) | ABCG2NPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160277-B | Apigenin derivative and application thereof | 中南大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-115160277-A | Apigenin derivative and application thereof | 中南大学 | 2022-10-11 | — | — | CN | disclosed |