Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 3/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660005 | 0.91 | TBXA2R (0.39) | MAPK1L3MBTL1TSHRPTGFRTBXA2R | |
| SCHEMBL11661648 | 0.89 | ADRB2 (0.41) | L3MBTL1TSHRPTGFRTBXA2RPTGER1 | |
| SCHEMBL11658825 | 0.89 | TSHR (0.45) | MAPK1L3MBTL1TSHRTDP1PTGFR | |
| SCHEMBL11656948 | 0.88 | TBXA2R (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11661929 | 0.88 | PTGFR (0.51) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11660150 | 0.88 | TBXA2R (0.39) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11657211 | 0.88 | TBXA2R (0.39) | TSHRPTGFRTBXA2RPTGER1PTGER3 | |
| SCHEMBL11658722 | 0.86 | MAPK1 (0.46) | MAPK1L3MBTL1TSHRTDP1PTGFR | |
| SCHEMBL11660214 | 0.86 | TBXA2R (0.38) | PTGFRTBXA2RPTGER1PTGER3PTGER2 | |
| SCHEMBL11656818 | 0.85 | PTGFR (0.41) | PTGFRTBXA2RPTGER1PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |