Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660005 | 0.90 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11658825 | 0.90 | TSHR (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11661648 | 0.90 | ADRB2 (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11657211 | 0.89 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11661929 | 0.89 | PTGFR (0.51) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11656948 | 0.89 | TBXA2R (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11661132 | 0.88 | MAPT (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11656818 | 0.88 | PTGFR (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11657915 | 0.88 | MAPK1 (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11660214 | 0.87 | TBXA2R (0.38) | TBXA2RPTGER1PTGFRPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |