Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | PTGFR | P43088 | 2/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661648 | 0.88 | ADRB2 (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11658825 | 0.88 | TSHR (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11660005 | 0.88 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11660150 | 0.87 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11657211 | 0.87 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11661929 | 0.87 | PTGFR (0.51) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11656948 | 0.87 | TBXA2R (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11660369 | 0.87 | PTGER1 (0.45) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11657915 | 0.86 | MAPK1 (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 | |
| SCHEMBL11660190 | 0.85 | PRMT5 (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |