Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | PTGFR | P43088 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661132 | 0.86 | MAPT (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11657643 | 0.86 | PTGER1 (0.40) | GRM2CASRTBXA2RPTGER1PTGFR | |
| SCHEMBL11660150 | 0.85 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11661648 | 0.82 | ADRB2 (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11658825 | 0.82 | TSHR (0.45) | CASRTBXA2RPTGER1PTGFRPTGER3 | |
| SCHEMBL11660005 | 0.82 | TBXA2R (0.39) | PPARGPPARATBXA2RPTGER1PTGFR | |
| SCHEMBL11661929 | 0.81 | PTGFR (0.51) | PPARGCASRTBXA2RPTGER1PTGFR | |
| SCHEMBL11656948 | 0.81 | TBXA2R (0.41) | TBXA2RPTGER1PTGFRPTGER3PTGDR | |
| SCHEMBL11661119 | 0.81 | NFKB1 (0.38) | GRM2PPARGCASRTBXA2RPTGER1 | |
| SCHEMBL11657211 | 0.81 | TBXA2R (0.39) | TBXA2RPTGER1PTGFRPTGER3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126629-A | FERTILITY CONTROL | MERCK & CO., INC. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4061643-A | ANTIFERTILITY | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4020177-A | CONTRACEPTIVES | MERCK & CO., INC. (US) | 1977-04-26 | — | — | US | disclosed |