Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640165 | 0.76 | LCK (0.48) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL10068398 | 0.76 | LCK (0.48) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL5965619 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL2776377 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL8370010 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| Hydrochloric Acid SCHEMBL11246895 | 0.73 | ALDH1A1 (0.46) | ALDH1A1TSHRLCKPPARDZDHHC20 | |
| SCHEMBL7139405 | 0.72 | — | — | |
| SCHEMBL17300148 | 0.71 | KIF11 (0.50) | ALDH1A1 | |
| SCHEMBL17308179 | 0.71 | GABRR1 (0.50) | — | |
| SCHEMBL2122342 | 0.71 | LCK (0.65) | ALDH1A1TSHRLCKPPARDZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4024182-A | Preparation of aryl-butadienoic acids | SANDOZ, INC. (US) | 1977-05-17 | — | — | US | disclosed |
| US-4011339-A | ANTIINFLAMMATORY AGENTS | SANDOZ, INC. (US) | 1977-03-08 | — | — | US | disclosed |