Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656912 | 0.83 | ALOX5 (0.38) | ALDH1A1NPSR1MEN1KMT2APOLB | |
| SCHEMBL9779583 | 0.74 | ALDH1A1 (0.41) | ALDH1A1NPSR1MEN1KMT2ANPC1 | |
| SCHEMBL10388765 | 0.72 | ALOX5 (0.46) | ALDH1A1MEN1KMT2AL3MBTL1POLB | |
| SCHEMBL10493058 | 0.71 | ALOX5 (0.45) | ALDH1A1NPSR1L3MBTL1POLBALOX5 | |
| SCHEMBL11522039 | 0.71 | ALOX5 (0.45) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6975656 | 0.69 | ALDH1A1 (0.42) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14143065 | 0.69 | ALDH1A1 (0.42) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11662979 | 0.68 | SMN1; SMN2 (0.47) | ALDH1A1PKMTACR3TSHRALOX15 | |
| SCHEMBL2859011 | 0.67 | ALDH1A1 (0.43) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2859012 | 0.67 | ALDH1A1 (0.43) | ALDH1A1NPSR1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097670-A | ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1978-06-27 | — | — | US | disclosed |