Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769954 | 0.88 | ALOX5 (0.42) | ALDH1A1SMN1; SMN2ALOX5MEN1KMT2A | |
| SCHEMBL9779441 | 0.83 | ALOX5 (0.39) | SMN1; SMN2ALOX5NPSR1POLBMAPT | |
| Hydrochloric Acid SCHEMBL9326175 | 0.79 | ALOX5 (0.41) | ALDH1A1PKMALOX5NPSR1POLB | |
| SCHEMBL14143065 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2PKMALOX5MEN1 | |
| SCHEMBL6975656 | 0.76 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2PKMALOX5MEN1 | |
| SCHEMBL9779355 | 0.75 | CYP2C19 (0.43) | ALDH1A1SMN1; SMN2ALOX5KMT2ANPSR1 | |
| SCHEMBL11659691 | 0.74 | ALDH1A1 (0.40) | ALDH1A1PKMALOX5MEN1KMT2A | |
| SCHEMBL4152673 | 0.73 | TACR3 (0.40) | NPSR1POLB | |
| SCHEMBL8760984 | 0.72 | ALOX5 (0.40) | ALDH1A1PKMALOX5KMT2ANPSR1 | |
| SCHEMBL8255644 | 0.72 | ALOX5 (0.47) | ALDH1A1ALOX5NPSR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |