Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.34 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662492 | 0.92 | CACNA1C (0.47) | CACNA1CSCN5AALDH1A1KDM4EHTT | |
| SCHEMBL10730044 | 0.90 | CACNA1C (0.53) | CACNA1CSCN5AALDH1A1KDM4EHTT | |
| SCHEMBL11656259 | 0.88 | CACNA1C (0.57) | CACNA1CSCN5AALDH1A1KDM4EHTT | |
| SCHEMBL11661996 | 0.88 | MEN1 (0.38) | ALDH1A1KDM4EHTTALOX15TDP1 | |
| SCHEMBL11663499 | 0.87 | CACNA1C (0.40) | CACNA1CSCN5AALDH1A1KDM4EHTT | |
| SCHEMBL11659898 | 0.86 | HTT (0.37) | CACNA1CSCN5AHTTNLRP3 | |
| SCHEMBL11839275 | 0.83 | HTT (0.36) | HTTBIDMCL1BCL2L1BAK1 | |
| SCHEMBL11665149 | 0.82 | CACNA1C (0.50) | CACNA1CSCN5AALDH1A1KDM4EHTT | |
| SCHEMBL11844367 | 0.82 | LIPG (0.38) | HTTALOX15TSHRTDP1BID | |
| SCHEMBL11835524 | 0.82 | LIPG (0.38) | HTTALOX15TSHRTDP1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117165-A | ANTIULCER, HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-09-26 | — | — | US | disclosed |