Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060963 | 0.82 | ATAD2 (0.41) | MMP8MMP14CA14RAB9ACA2 | |
| SCHEMBL11070782 | 0.81 | MEN1 (0.46) | MMP8MMP14CA14EPHX1NPC1 | |
| SCHEMBL1555336 | 0.79 | MMP8 (0.53) | MMP8MMP14CA14EPHX1EPHX2 | |
| SCHEMBL733499 | 0.79 | MMP8 (0.53) | MMP8MMP14CA14EPHX1EPHX2 | |
| SCHEMBL736304 | 0.79 | MMP8 (0.53) | MMP8MMP14CA14EPHX1EPHX2 | |
| SCHEMBL11069740 | 0.79 | RAB9A (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL11196619 | 0.77 | MMP8 (0.50) | MMP8MMP14CA14EPHX1EPHX2 | |
| SCHEMBL11196634 | 0.77 | MMP8 (0.50) | MMP8MMP14CA14EPHX1EPHX2 | |
| SCHEMBL11059295 | 0.75 | EPHX1 (0.48) | EPHX1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL734621 | 0.75 | CYP3A4 (0.53) | MMP8MMP14CA14EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087535-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | disclosed |
| US-4061767-A | ANTIINFLAMMATORY, ANALGESIC | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |