Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.48 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660637 | 1.00 | BACE1 (0.49) | BACE1NPY1RNPY2RNPY4RUTS2R | |
| SCHEMBL29367998 | 0.99 | BACE1 (0.49) | BACE1NPY1RNPY2RNPY4RUTS2R | |
| SCHEMBL24270257 | 0.91 | MMP2 (0.52) | BACE1NPY1RNPY2RNPY4RUTS2R | |
| SCHEMBL30688844 | 0.91 | MMP2 (0.55) | BACE1NPY1RNPY2RNPY4RGNPAT | |
| SCHEMBL31602281 | 0.91 | GNPAT (0.57) | GNPATMMP2OPRK1 | |
| SCHEMBL29389091 | 0.90 | MMP2 (0.51) | BACE1NPY1RNPY2RNPY4RUTS2R | |
| SCHEMBL31602283 | 0.87 | CTSL (0.55) | MMP2OPRK1 | |
| SCHEMBL30799638 | 0.87 | MMP2 (0.56) | BACE1NPY1RNPY2RNPY4RGNPAT | |
| SCHEMBL29679650 | 0.87 | ERAP2 (0.55) | BACE1GNPATMMP2OPRK1 | |
| SCHEMBL30889681 | 0.87 | MME (0.56) | MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081530-A | Extended chain derivatives of somatostatin | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-03-28 | — | — | US | disclosed |