SCHEMBL29367998

SCHEMBL29367998

NCCCC[C@H](NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ BACE1 P56817 2/20 0.49
▸ MMP2 P08253 1/20 0.48
▸ NPY1R P25929 1/20 0.47
▸ NPY2R P49146 1/20 0.47
▸ NPY4R P50391 1/20 0.47
▸ UTS2R Q9UKP6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11660637 0.99 BACE1 (0.49) BACE1MMP2NPY1RNPY2RNPY4R
SCHEMBL11660631 0.99 BACE1 (0.49) BACE1MMP2NPY1RNPY2RNPY4R
SCHEMBL24270257 0.89 MMP2 (0.52) BACE1MMP2NPY1RNPY2RNPY4R
SCHEMBL30688844 0.89 MMP2 (0.55) BACE1MMP2NPY1RNPY2RNPY4R
SCHEMBL31602281 0.89 GNPAT (0.57) MMP2
SCHEMBL29389091 0.89 MMP2 (0.51) BACE1MMP2NPY1RNPY2RNPY4R
SCHEMBL29679650 0.88 ERAP2 (0.55) BACE1MMP2
SCHEMBL10520779 0.88 GHSR (0.54) BACE1MMP2
SCHEMBL30799638 0.86 MMP2 (0.56) BACE1MMP2NPY1RNPY2RNPY4R
SCHEMBL31602283 0.86 CTSL (0.55) MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases BCN PEPTIDES, S.A. (ES) 2025-05-13 — — US claimed
EP-4583873-A2 GENETICALLY ENGINEERED HUMAN PITUITARY CORTICOTROPH TUMOR ORGANOIDS EXHIBIT DIVERGENT RESPONSES TO SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS Corcept Therapeutics Incorporated (US) 2025-07-16 — — EP disclosed
CN-120131956-A Use of growth hormone inhibitors, and pharmaceutical compositions, formulations, and devices containing growth hormone inhibitors 中山大学中山眼科中心 2025-06-13 — — CN disclosed
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases BCN PEPTIDES, S.A. (ES) 2025-05-13 — — US disclosed
CN-111886336-B CASZ compositions and methods of use 加利福尼亚大学董事会 2025-05-02 — — CN disclosed
CN-113652411-B Cas9 protein, gene editing system containing Cas9 protein and application 复旦大学 2025-01-10 — — CN disclosed
CN-114981296-B Recombinant GBD-SSTad-SSTad protein and preparation method and application thereof 优思药业有限责任公司 2024-12-03 — — CN disclosed
WO-2024054785-A2 GENETICALLY ENGINEERED HUMAN PITUITARY CORTICOTROPH TUMOR ORGANOIDS EXHIBIT DIVERGENT RESPONSES TO SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS CORCEPT THERAPEUTICS INCORPORATED (US) 2024-03-14 — — WO disclosed
CN-112020560-B RNA-edited CRISPR/Cas effect protein and system 中国农业大学 2024-02-23 — — CN disclosed
CN-111388680-B Application of polypeptide complex as polypeptide or protein drug carrier, method and fusion protein complex thereof 中国科学院天津工业生物技术研究所 2024-01-05 — — CN disclosed
CN-114814241-A Use of protein and screening method 广东省农业科学院动物科学研究所 2022-07-29 — — CN disclosed
CN-111617250-B Multi-ligand drug couplet and application thereof 同宜医药(苏州)有限公司 2022-07-01 — — CN disclosed
CN-114621982-A Biosynthesis method of geranyl diphosphate and application of geranyl diphosphate in preparation of cannabis compounds 嘉兴欣贝莱生物科技有限公司 2022-06-14 — — CN disclosed
CN-114555792-A Recombinant engineered, lipase/esterase deficient mammalian cell lines 伊莱利利公司 2022-05-27 — — CN disclosed
CN-114480340-A Halophilic choline kinase mutant and application thereof 郑州大学 2022-05-13 — — CN disclosed
US-20220135640-A1 CORTISTATIN OR AN ANALOGUE THEREOF AS A PHARMACEUTICALLY ACTIVE AGENT IN LATENT FORM CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) 2022-05-05 — — US disclosed
CN-114410675-A Recombinant strain containing enol kinase gene and isopentenyl phosphate kinase gene and application thereof in production of terpenoid 深圳先进技术研究院 2022-04-29 — — CN disclosed
CN-108135993-B Pestivirus vaccine for congenital tremor 贝林格尔·英格海姆维特梅迪卡有限公司 2022-03-22 — — CN disclosed
CN-112533936-B Method for purifying peptide using sulfonic acid compound 长濑产业株式会社 2022-03-01 — — CN disclosed
CN-109311910-B Tacrolimus conjugates, compositions thereof, and uses thereof 杜兰教育基金委员会 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12297294-B2 Cortistatin analogues for the treatment of inflammatory and/or immune diseases GHSR, GIPR, GHRHR BACE1 2464/4885MMP2 2068/4885NPY1R 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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