Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11660741 | 0.82 | KDM4E (0.43) | IDO1TAAR1LOXL2AOC3 | |
| SCHEMBL11663043 | 0.80 | IDO1 (0.49) | IDO1TDO2TAAR1AOC3 | |
| SCHEMBL11661946 | 0.77 | TAAR1 (0.53) | IDO1HTR2ATAAR1TSHR | |
| SCHEMBL7782094 | 0.75 | TSHR (0.44) | SMN1; SMN2TSHRHPGD | |
| SCHEMBL7265649 | 0.75 | ANPEP (0.47) | ANPEPERAP1MMP12ERAP2IDO1 | |
| SCHEMBL873038 | 0.74 | MMP12 (0.45) | ANPEPERAP1MMP12ERAP2CYP2A6 | |
| SCHEMBL13074081 | 0.74 | MMP12 (0.57) | ANPEPERAP1MMP12ERAP2TAAR1 | |
| SCHEMBL820953 | 0.72 | TSHR (0.46) | MMP12SMN1; SMN2G6PDTSHRHPGD | |
| SCHEMBL13626178 | 0.72 | TSHR (0.46) | MMP12SMN1; SMN2G6PDTSHRHPGD | |
| SCHEMBL11662165 | 0.72 | LMNA (0.50) | SMN1; SMN2TAAR1AOC3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |