Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820953 | 1.00 | TSHR (0.46) | TSHRG6PDPOLBMMP12ALDH1A1 | |
| SCHEMBL7181668 | 0.88 | PDE4A (0.46) | — | |
| SCHEMBL585331 | 0.84 | TSHR (0.47) | TSHRPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL837629 | 0.81 | TSHR (0.44) | TSHRPOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL873038 | 0.80 | MMP12 (0.45) | TSHRG6PDPOLBMMP12ALDH1A1 | |
| SCHEMBL13074081 | 0.80 | MMP12 (0.57) | TSHRG6PDPOLBMMP12ALDH1A1 | |
| SCHEMBL2555409 | 0.79 | SIGMAR1 (0.56) | MEN1KMT2AOPRK1 | |
| SCHEMBL13189946 | 0.79 | SIGMAR1 (0.56) | MEN1KMT2AOPRK1 | |
| SCHEMBL13006663 | 0.79 | SIGMAR1 (0.56) | MEN1KMT2AOPRK1 | |
| SCHEMBL13713720 | 0.79 | ESR1 (0.50) | TSHRCYP1A2MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009136281-A1 | NITRIC OXIDE DONATING PROSTAMIDES | NICOX S.A. (FR) | 2009-11-12 | — | — | WO | disclosed |