Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662610 | 0.85 | JMJD6 (0.63) | JMJD6HTR4PIK3CACARM1PRMT6 | |
| SCHEMBL11659023 | 0.79 | KDM4E (0.53) | JMJD6KDM4EALDH1A1MAPTCARM1 | |
| SCHEMBL28897674 | 0.78 | L3MBTL1 (0.50) | KDM4EALDH1A1PTGIR | |
| SCHEMBL930636 | 0.78 | JMJD6 (0.57) | JMJD6KDM5AKDM5CKDM4CKDM5B | |
| SCHEMBL29466587 | 0.78 | JMJD6 (0.57) | JMJD6KDM5AKDM5CKDM4CKDM5B | |
| SCHEMBL15134549 | 0.77 | PARP10 (0.48) | JMJD6PARP15PARP10PARP2 | |
| SCHEMBL11661187 | 0.77 | MAPK1 (0.50) | JMJD6KDM4EPARP15PARP10PARP2 | |
| SCHEMBL8406007 | 0.75 | JMJD6 (0.59) | JMJD6KDM4EKDM6BTET3KDM4A | |
| SCHEMBL11664026 | 0.75 | TSHR (0.56) | KDM4EALDH1A1MAPT | |
| SCHEMBL28196739 | 0.74 | P2RX7 (0.46) | JMJD6PARP15PARP10PARP2PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093622-A | Pyridine esters of cyclopropane-carboxylic acid | ZOECON CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |