Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665135 | 0.86 | PNMT (0.41) | PNMTNR3C1TAAR1CYP3A4IDO1 | |
| SCHEMBL11663079 | 0.83 | HTR2A (0.47) | TAAR1IDO1 | |
| SCHEMBL11661894 | 0.82 | TSHR (0.41) | NR3C1TAAR1CYP3A4TSHR | |
| SCHEMBL11515564 | 0.78 | TSHR (0.40) | PNMTTAAR1CYP3A4IDO1AGXT | |
| SCHEMBL11664309 | 0.76 | PNMT (0.41) | PNMTNR3C1TAAR1CYP3A4IDO1 | |
| SCHEMBL11659218 | 0.75 | TAAR1 (0.33) | NR3C1TAAR1IDO1AGXTTSHR | |
| SCHEMBL11662620 | 0.72 | HTR2A (0.47) | TAAR1IDO1 | |
| SCHEMBL11611733 | 0.71 | TAAR1 (0.42) | PNMTTAAR1CYP3A4TSHRRECQL | |
| SCHEMBL11516606 | 0.70 | PNMT (0.43) | PNMTTAAR1CYP3A4IDO1AGXT | |
| SCHEMBL11613482 | 0.70 | TSHR (0.43) | PNMTTAAR1TSHRRECQLPYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |