Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662003 | 0.86 | PNMT (0.40) | PNMTCYP3A4IDO1AGXTNR3C1 | |
| SCHEMBL11659374 | 0.81 | TRPA1 (0.47) | CYP3A4TAAR1MAOBTSHR | |
| SCHEMBL11613482 | 0.81 | TSHR (0.43) | PNMTTAAR1ENPP2PKMTSHR | |
| SCHEMBL11662620 | 0.80 | HTR2A (0.47) | IDO1TAAR1MAOB | |
| SCHEMBL11662794 | 0.77 | PNMT (0.41) | PNMTCYP3A4IDO1AGXTNR3C1 | |
| SCHEMBL11661775 | 0.73 | RELA (0.35) | MAOB | |
| SCHEMBL11663075 | 0.72 | CASR (0.35) | IDO1AGXTNR3C1MAOB | |
| SCHEMBL11663043 | 0.72 | IDO1 (0.49) | PNMTCYP3A4IDO1AGXTTAAR1 | |
| SCHEMBL11614808 | 0.72 | PNMT (0.46) | PNMTCYP3A4IDO1AGXTTAAR1 | |
| SCHEMBL73643 | 0.71 | PNMT (0.54) | PNMTCYP3A4IDO1AGXTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |