Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661894 | 0.85 | TSHR (0.41) | TAAR1TRPA1NR3C1TSHR | |
| SCHEMBL11663075 | 0.85 | CASR (0.35) | CASRIDO1AGXTAOC3TRPA1 | |
| SCHEMBL11663079 | 0.75 | HTR2A (0.47) | TAAR1IDO1MAOB | |
| SCHEMBL11662003 | 0.75 | PNMT (0.40) | TAAR1IDO1AGXTAOC3NR3C1 | |
| SCHEMBL11611923 | 0.75 | CASR (0.34) | TAAR1CASRIDO1AGXTAOC3 | |
| SCHEMBL11664314 | 0.72 | TAAR1 (0.34) | TAAR1CASRIDO1AGXTAOC3 | |
| SCHEMBL11664076 | 0.69 | NFE2L2 (0.37) | CASR | |
| SCHEMBL11659374 | 0.68 | TRPA1 (0.47) | TAAR1CASRTRPA1MAOBTSHR | |
| SCHEMBL11518178 | 0.67 | TRPA1 (0.39) | CASRIDO1TRPA1LOXL2MAOB | |
| SCHEMBL11660741 | 0.67 | KDM4E (0.43) | TAAR1IDO1AGXTAOC3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |