Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661597 | 0.87 | HTR2A (0.48) | HTR2AHTR2BHTR2CMAOBIDO1 | |
| SCHEMBL11614193 | 0.80 | HTR2A (0.49) | HTR2AHTR2BHTR2CMAOBIDO1 | |
| SCHEMBL11662794 | 0.80 | PNMT (0.41) | MAOBIDO1TAAR1 | |
| SCHEMBL11766837 | 0.80 | HTR2A (0.46) | HTR2AHTR2BHTR2CMAOBIDO1 | |
| SCHEMBL11662206 | 0.79 | TRPA1 (0.47) | MAOBTAAR1LMNA | |
| SCHEMBL11662620 | 0.78 | HTR2A (0.47) | HTR2AHTR2BHTR2CMAOBIDO1 | |
| SCHEMBL11663978 | 0.76 | L3MBTL1 (0.41) | HTR2AHTR2BHTR2CMAOBLMNA | |
| SCHEMBL11616015 | 0.75 | IDO1 (0.50) | HTR2AHTR2BHTR2CMAOBIDO1 | |
| SCHEMBL73993 | 0.73 | HTR2A (0.58) | HTR2AHTR2BHTR2CMAOBIDO1 | |
| SCHEMBL11664090 | 0.73 | TAAR1 (0.50) | HTR2AHTR2BHTR2CMAOBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |