Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662762 | 0.84 | TRPA1 (0.36) | TRPA1HPGDKDM4ENR3C1NR3C2 | |
| SCHEMBL11665884 | 0.84 | SLC6A2 (0.42) | TRPA1NR3C1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11665621 | 0.74 | HPGD (0.36) | TRPA1HPGDKDM4ENR3C1NR3C2 | |
| SCHEMBL11659464 | 0.73 | NR3C1 (0.43) | NR3C1RIPK1 | |
| SCHEMBL4930066 | 0.73 | ESR1 (0.43) | TRPA1HPGDKDM4ERIPK1CYP3A4 | |
| SCHEMBL11663131 | 0.71 | TAAR1 (0.38) | ESR1IDO1 | |
| SCHEMBL700506 | 0.71 | PYCR1 (0.42) | TRPA1HPGDKDM4ERIPK1CYP3A4 | |
| SCHEMBL11664083 | 0.70 | PTGS1 (0.43) | TRPA1HPGDKDM4ECYP3A4CYP2D6 | |
| SCHEMBL31416623 | 0.70 | HPGD (0.41) | TRPA1HPGDKDM4ERIPK1CYP3A4 | |
| SCHEMBL28210190 | 0.70 | HPGD (0.41) | TRPA1HPGDKDM4ERIPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |