Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11664145 | 1.00 | ERN1 (0.41) | ERN1CYP3A4TDP1CDK4CCND1 | |
| SCHEMBL22171539 | 0.83 | CYP3A4 (0.50) | ERN1CYP3A4TDP1TP53SMN1; SMN2 | |
| SCHEMBL19113609 | 0.81 | CYP3A4 (0.41) | ERN1CYP3A4TDP1TP53SMN1; SMN2 | |
| SCHEMBL14384897 | 0.80 | ALOX5 (0.50) | ERN1TDP1CDK4CCND1SMN1; SMN2 | |
| SCHEMBL28908860 | 0.80 | TDP1 (0.47) | ERN1CYP3A4TDP1CDK4CCND1 | |
| SCHEMBL28908861 | 0.80 | TDP1 (0.47) | ERN1CYP3A4TDP1CDK4CCND1 | |
| SCHEMBL29957786 | 0.79 | ERN1 (0.57) | ERN1CYP3A4TDP1TP53SMN1; SMN2 | |
| SCHEMBL692253 | 0.79 | ERN1 (0.57) | ERN1CYP3A4TDP1TP53SMN1; SMN2 | |
| SCHEMBL22039183 | 0.78 | ERN1 (0.42) | ERN1TDP1CDK4CCND1ALDH1A1 | |
| SCHEMBL20109997 | 0.78 | CYP3A4 (0.45) | ERN1CYP3A4TDP1ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087549-A | Sulphonic acid containing indenyl derivatives | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |