Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692253 | 1.00 | ERN1 (0.57) | ERN1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL269702 | 0.82 | TDP1 (0.61) | ERN1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL22171539 | 0.81 | CYP3A4 (0.50) | ERN1TDP1ALDH1A1CYP3A4TP53 | |
| SCHEMBL11664145 | 0.79 | ERN1 (0.41) | ERN1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL11664142 | 0.79 | ERN1 (0.41) | ERN1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL28030980 | 0.79 | CYP3A4 (0.48) | ERN1TDP1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL4357334 | 0.78 | TDP1 (0.70) | ERN1TDP1ALDH1A1HPGDTP53 | |
| SCHEMBL2559192 | 0.78 | RAPGEF4 (0.51) | ERN1TDP1ALDH1A1TSHRLMNA | |
| SCHEMBL7820969 | 0.77 | CYP3A4 (0.46) | ERN1TDP1ALDH1A1CYP3A4TP53 | |
| SCHEMBL6258762 | 0.77 | CYP3A4 (0.46) | ERN1TDP1ALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |