SCHEMBL11664339

SCHEMBL11664339

COP(=O)(CNC(=O)NCP(=O)(OC)OC)OC

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30
EPHX1 P07099 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11038208 0.83 EPHX1 (0.39) TSHRL3MBTL1MMP1MMP2MMP3
SCHEMBL11664384 0.83 KDM4E (0.37) TSHRGAAMMP1ALDH1A1
SCHEMBL11775958 0.81 TSHR (0.41) TSHRGAAMEN1KMT2AALDH1A1
SCHEMBL11744422 0.81 TDP1 (0.32)
SCHEMBL8677873 0.76 ALDH1A1 (0.38) ALDH1A1
SCHEMBL11775049 0.76 CASP2 (0.42) TSHR
SCHEMBL977677 0.76 TSHR (0.46) TSHRGAAALDH1A1
SCHEMBL11129649 0.76 KDM4E (0.42) TSHRGAAKMT2AALDH1A1
SCHEMBL11775444 0.76 TSHR (0.37) TSHR
SCHEMBL11662270 0.75 FPR2 (0.44) MMP1MMP8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220127533-A1 PHOSPHORUS NITROGEN FLAME RETARDANT, METHOD THEREOF AND MATERIAL COMPRISING THE SAME ZHOU CHONGFU (US) 2022-04-28 US disclosed
US-4090959-A A PHOSPHONATE-SUBSTITUTED METHANESULFONAMIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-05-23 US disclosed
US-4055591-A METAL ION SEQUESTRANTS, FLAME RETARDANTS HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-10-25 US disclosed
US-3992294-A UREAPHOSPHONATES HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-11-16 US disclosed
US-3939226-A SEQUESTRANT, FIRE RETARDANT HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-02-17 US disclosed