Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661653 | 0.88 | TRPA1 (0.44) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL11658647 | 0.85 | MEN1 (0.50) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL11662075 | 0.76 | TRPA1 (0.46) | ALDH1A1HTTALOX15HSD17B10TRPA1 | |
| SCHEMBL5988956 | 0.74 | TRPA1 (0.47) | MEN1KMT2AALDH1A1HTTALOX15 | |
| SCHEMBL5988961 | 0.74 | TRPA1 (0.47) | MEN1KMT2AALDH1A1HTTALOX15 | |
| SCHEMBL5988966 | 0.74 | TRPA1 (0.47) | MEN1KMT2AALDH1A1HTTALOX15 | |
| SCHEMBL11659597 | 0.72 | MAPT (0.52) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL5988981 | 0.71 | TRPA1 (0.50) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL7565930 | 0.70 | TRPA1 (0.61) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL29779649 | 0.69 | ALDH1A1 (0.42) | MEN1KMT2AHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122194-A | Aryl sulphur compounds as antiasthmatics | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |