Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988956 | 1.00 | TRPA1 (0.47) | TRPA1ALDH1A1MAPTGAAALOX15 | |
| SCHEMBL5988961 | 1.00 | TRPA1 (0.47) | TRPA1ALDH1A1MAPTGAAALOX15 | |
| SCHEMBL11662075 | 0.86 | TRPA1 (0.46) | TRPA1ALDH1A1MAPTGAAALOX15 | |
| SCHEMBL11661653 | 0.84 | TRPA1 (0.44) | TRPA1ALDH1A1MAPTGAAALOX15 | |
| SCHEMBL11664402 | 0.74 | MEN1 (0.37) | TRPA1ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL6054881 | 0.73 | PPARG (0.33) | ALDH1A1MAPTCYP1A2CYP2A6TP53 | |
| SCHEMBL9563677 | 0.73 | ALDH1A1 (0.39) | TRPA1ALDH1A1MAPTALOX15KDM4E | |
| SCHEMBL5989715 | 0.72 | PPARG (0.38) | CYP1A2CYP2A6 | |
| SCHEMBL5988927 | 0.72 | PPARG (0.38) | CYP1A2CYP2A6 | |
| SCHEMBL5989709 | 0.72 | PPARG (0.38) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |