Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350620 | 0.94 | KDM4E (0.58) | KDM4EMAPK1HIF1AGPR84FFAR1 | |
| SCHEMBL28351020 | 0.92 | KDM4E (0.61) | KDM4EMAPK1HIF1AGPR84FFAR1 | |
| SCHEMBL11686140 | 0.87 | MTNR1A (0.50) | KDM4EMAPK1HIF1AGPR84FFAR1 | |
| SCHEMBL11686147 | 0.87 | MTNR1A (0.50) | KDM4EMAPK1HIF1AGPR84FFAR1 | |
| SCHEMBL18125979 | 0.83 | GPR84 (0.48) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL3346616 | 0.79 | GPR84 (0.45) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL3347293 | 0.79 | GPR84 (0.45) | GPR84FFAR1TET2KDM4AKDM4C | |
| SCHEMBL24810742 | 0.78 | KDM4E (0.58) | KDM4EMAPK1HIF1AADRA1AFOLH1 | |
| SCHEMBL12601501 | 0.78 | KDM4E (0.64) | KDM4EMAPK1HIF1AADRA1AFOLH1 | |
| SCHEMBL2238055 | 0.78 | OTC (0.57) | KDM4EMAPK1HIF1AADRA1APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53015317-A | — | — | None | — | — | JP | disclosed |
| JP-S5315317-A | 5-ACETOAMINO-2-HYDROXYVALERIC ACID, ITS LOWER ESTERS, AND MODIFIER OF SMOKING TASTE OF TOBACCO CONTAINING SAID COMPOUNDS | JAPAN TOBACCO INC | 1978-02-13 | — | — | JP | disclosed |