Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567085 | 0.80 | MAPK1 (0.81) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL12302132 | 0.76 | ALDH1A1 (0.90) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL18770137 | 0.76 | MEN1 (0.38) | ALDH1A1LMNASMN1; SMN2PKMMEN1 | |
| SCHEMBL31014207 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL29967391 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL24762147 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2446255 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL386724 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL3126117 | 0.74 | ALDH1A1 (0.75) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL13159473 | 0.74 | ALDH1A1 (0.94) | ALDH1A1LMNAHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53065881-A | — | — | None | — | — | JP | disclosed |
| JP-S5365881-A | PYRIDINE-3-SULFONEAMIDE-1-OXIDE DERIVS. AND ANTICOCCIDIOSIS AGENTS CONTAININGTHE SAME AS ACTIVE CONSTITUENTS | SANKYO CO LTD | 1978-06-12 | — | — | JP | disclosed |