Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 7/20 | 0.49 |
| ▸ | THRB | P10828 | 7/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11657847 | 0.81 | LOXL2 (0.42) | MRGPRX4ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11346502 | 0.78 | THRA (0.47) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL9173276 | 0.77 | HTT (0.47) | ESR1NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9177519 | 0.75 | MAPT (0.44) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL11662582 | 0.74 | THRA (0.43) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL11658327 | 0.73 | RXRA (0.44) | THRATHRBNPC1ALDH1A1RAB9A | |
| SCHEMBL4887098 | 0.71 | THRA (0.69) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL28598401 | 0.70 | GAA (0.65) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL11654831 | 0.70 | MAPT (0.42) | THRATHRBESR1NR3C1PGR | |
| SCHEMBL9368330 | 0.70 | MRGPRX4 (0.76) | MRGPRX4NPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105628-A | HALOGEN-CONTAINING AROMATIC ETHER-ESTER FIRE-RETARDANTS FOR PLASTICS | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1978-08-08 | — | — | US | disclosed |