Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063425 | 0.69 | ITGB1 (0.52) | TSHRGABRR1GABRR2BLMLMNA | |
| SCHEMBL472480 | 0.69 | ALDH1A1 (0.72) | ALDH1A1MAPTPOLBHPGDTSHR | |
| SCHEMBL7646672 | 0.68 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBHPGDTSHR | |
| SCHEMBL17294189 | 0.67 | ALDH1A1 (0.69) | ALDH1A1MAPTPOLBHPGDTSHR | |
| SCHEMBL25132278 | 0.66 | GAA (0.41) | ALDH1A1MAPTTSHRRGS12GAA | |
| SCHEMBL17930204 | 0.65 | HSD17B10 (0.42) | ALDH1A1MAPTHPGDTSHRLMNA | |
| SCHEMBL6745338 | 0.64 | HSD17B10 (0.37) | ALDH1A1MAPTTSHRLMNAHSD17B10 | |
| SCHEMBL29218708 | 0.61 | GABRR1 (0.35) | ALDH1A1MAPTPOLBTSHRGABRR1 | |
| SCHEMBL2064738 | 0.61 | TSHR (0.42) | ALDH1A1MAPTTSHRLMNATDP1 | |
| SCHEMBL9227344 | 0.61 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101549-A | Aminophenyl esters of 5-carboxyalkyl barbituric acids | HOFFMANN-LA ROCHE INC. (US) | 1978-07-18 | — | — | US | disclosed |