Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17930204 | 0.68 | HSD17B10 (0.42) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL11666010 | 0.64 | ALDH1A1 (0.53) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL9227344 | 0.64 | ALDH1A1 (0.38) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL145905 | 0.62 | TSHR (0.46) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL11373401 | 0.62 | HSD17B10 (0.50) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL533616 | 0.62 | HSD17B10 (0.37) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL7646486 | 0.62 | HSD17B10 (0.37) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL6977803 | 0.62 | GRM2 (0.37) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL17898549 | 0.62 | IDO1 (0.40) | HSD17B10MAPTALDH1A1LMNAHTT | |
| SCHEMBL2162536 | 0.60 | ALDH1A1 (0.42) | HSD17B10MAPTALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772770-B2 | DETERMINING BIODEGRADABILITY OF IMINODIACETIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2004-02-11 | — | — | EP | disclosed |
| EP-0772770-B1 | DETERMINING BIODEGRADABILITY OF IMINODIACETIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2000-04-05 | — | — | EP | disclosed |