Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566351 | 0.97 | ACHE (0.52) | POLBKDM4EACHESMN1; SMN2NPC1 | |
| SCHEMBL13261464 | 0.85 | SMN1; SMN2 (0.52) | POLBKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL28791442 | 0.83 | ALDH1A1 (0.54) | POLBKDM4EACHESMN1; SMN2NPC1 | |
| SCHEMBL6890994 | 0.81 | POLB (0.54) | POLBKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL3896033 | 0.81 | SMN1; SMN2 (0.55) | POLBKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11653596 | 0.80 | SMN1; SMN2 (0.58) | POLBKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL4952423 | 0.80 | ACHE (0.60) | POLBKDM4EACHESMN1; SMN2ALDH1A1 | |
| SCHEMBL875632 | 0.79 | ALOX15 (0.57) | POLBKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL7336195 | 0.78 | PPARG (0.53) | POLBKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL2364767 | 0.78 | ESR1 (0.60) | KDM4EACHESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4107324-A | ARTHROPODICIDES, FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-15 | — | — | US | disclosed |