Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846739 | 0.85 | HTR3A (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL11668633 | 0.81 | NPC1 (0.43) | CYP1A2CYP2C19KMT2AMEN1NPC1 | |
| SCHEMBL11606845 | 0.80 | — | — | |
| SCHEMBL11669344 | 0.76 | RECQL (0.34) | ALDH1A1 | |
| SCHEMBL11064817 | 0.76 | ALDH1A1 (0.45) | KMT2APOLBMEN1NPC1RAB9A | |
| SCHEMBL11668842 | 0.76 | HRH3 (0.37) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL11668916 | 0.74 | ALDH1A1 (0.33) | KMT2AMEN1PDE10AALDH1A1 | |
| SCHEMBL11669188 | 0.73 | KDM4E (0.34) | ALDH1A1HPGD | |
| SCHEMBL11275928 | 0.72 | HRH3 (0.40) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL11669273 | 0.72 | SMN1; SMN2 (0.34) | KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021554-A | 1,4-Oxathiino[2,3-c]pyrrole derivatives | RHONE-POULENC INDUSTRIES (FR) | 1977-05-03 | — | — | US | disclosed |