Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836845 | 0.82 | SCN2A (0.44) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL11669575 | 0.79 | NLRP3 (0.41) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11669554 | 0.75 | SCN2A (0.53) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL11836837 | 0.66 | HPN (0.43) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL11836629 | 0.66 | SCN2A (0.68) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL11669049 | 0.65 | KDM4E (0.34) | MAPTALDH1A1KDM4E | |
| SCHEMBL11668936 | 0.64 | NPC1 (0.31) | SMN1; SMN2 | |
| SCHEMBL15272586 | 0.64 | MAPT (0.60) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL4457140 | 0.63 | HPN (0.51) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL8096821 | 0.63 | HPN (0.48) | SCN2AHPNMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021554-A | 1,4-Oxathiino[2,3-c]pyrrole derivatives | RHONE-POULENC INDUSTRIES (FR) | 1977-05-03 | — | — | US | disclosed |