Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.68 |
| ▸ | HPN | P05981 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669554 | 0.85 | SCN2A (0.53) | SCN2AHPNALDH1A1NPSR1BCL2A1 | |
| SCHEMBL11669113 | 0.81 | SCN2A (1.00) | SCN2AHPNBCL2A1MEN1MAPT | |
| SCHEMBL30758587 | 0.81 | SCN2A (1.00) | SCN2AHPNBCL2A1MEN1MAPT | |
| SCHEMBL11211949 | 0.78 | SCN2A (0.66) | SCN2AHPNALDH1A1BCL2A1MEN1 | |
| SCHEMBL11836845 | 0.77 | SCN2A (0.44) | SCN2AHPNALDH1A1BCL2A1MEN1 | |
| SCHEMBL11842849 | 0.76 | ALDH1A1 (0.66) | ALDH1A1NPSR1BCL2A1MEN1MAPT | |
| SCHEMBL10854270 | 0.76 | HPN (0.68) | SCN2AHPNALDH1A1BCL2A1MEN1 | |
| SCHEMBL10381359 | 0.76 | SCN2A (0.82) | SCN2AHPNALDH1A1MEN1MAPT | |
| SCHEMBL11836622 | 0.75 | HPN (0.57) | SCN2AHPNALDH1A1BCL2A1MEN1 | |
| SCHEMBL2029909 | 0.74 | HPN (1.00) | SCN2AHPNALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966931-A | TRANQUILIZERS, ANTICONVULSANTS, HYPNOSIS | RHONE-POULENC S.A. (FR) | 1976-06-29 | — | — | US | disclosed |
| US-3948917-A | TRANQUILIZERS, ANTICONVULSANTS, DECONTRACTURANTS, HYPNOSIS | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |