Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836629 | 0.85 | SCN2A (0.68) | SCN2AHPNBCL2A1MEN1KMT2A | |
| SCHEMBL11669238 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11669285 | 0.75 | SCN2A (0.41) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL11064817 | 0.71 | ALDH1A1 (0.45) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11669113 | 0.70 | SCN2A (1.00) | SCN2AHPNBCL2A1MEN1KMT2A | |
| SCHEMBL30758587 | 0.70 | SCN2A (1.00) | SCN2AHPNBCL2A1MEN1KMT2A | |
| SCHEMBL11211949 | 0.70 | SCN2A (0.66) | SCN2AHPNBCL2A1MEN1KMT2A | |
| SCHEMBL10854270 | 0.69 | HPN (0.68) | SCN2AHPNBCL2A1MEN1KMT2A | |
| SCHEMBL10381359 | 0.68 | SCN2A (0.82) | SCN2AHPNMEN1KMT2AMAPT | |
| SCHEMBL11836622 | 0.68 | HPN (0.57) | SCN2AHPNBCL2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021554-A | 1,4-Oxathiino[2,3-c]pyrrole derivatives | RHONE-POULENC INDUSTRIES (FR) | 1977-05-03 | — | — | US | disclosed |