Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.76 |
| ▸ | MAOB | P27338 | 8/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625779 | 0.86 | MAOB (0.59) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL11515229 | 0.86 | MAOA (1.00) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL11669501 | 0.78 | ALDH1A1 (0.53) | MAOAMAOBMAPTHPGDMEN1 | |
| SCHEMBL11619404 | 0.77 | MAOA (0.49) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL11619406 | 0.77 | MAOA (0.49) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL2606189 | 0.77 | MAOA (0.81) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL29611540 | 0.77 | MAOA (0.81) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL11668781 | 0.75 | TDP2 (0.54) | MAOAMAOBATML3MBTL1MAPT | |
| SCHEMBL11670022 | 0.74 | MEN1 (0.48) | MAOAMAOBL3MBTL1MAPTTDP1 | |
| SCHEMBL31634592 | 0.74 | MAOA (0.66) | MAOAMAOBATML3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065462-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4016157-A | COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |