Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | PGR | P06401 | 5/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SHBG | P04278 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5173777 | 0.78 | NR1I2 (0.62) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL11669557 | 0.78 | PGR (0.42) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL5173779 | 0.78 | NR1I2 (0.62) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL9663211 | 0.78 | PGR (0.45) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL5074748 | 0.78 | PGR (0.45) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL3816344 | 0.74 | SERPINA6 (0.72) | LMNACYP3A4PGRNR3C1ESR1 | |
| SCHEMBL11852053 | 0.74 | SHBG (0.47) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL4108527 | 0.72 | PGR (0.53) | LMNACYP3A4SLC6A4PGRABCB11 | |
| SCHEMBL11699038 | 0.72 | SERPINA6 (0.71) | LMNACYP3A4PGRABCB11NR3C1 | |
| SCHEMBL6832273 | 0.72 | CYP19A1 (0.65) | SHBGALDH1A1SERPINA6SLC22A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014988-A | Method for treating hypermenorrhea with uterine therapeutic system | ALZA CORPORATION (US) | 1977-03-29 | — | — | US | claimed |