Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | PGR | P06401 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711002 | 0.84 | SERPINA6 (0.68) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL5076704 | 0.82 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL12446091 | 0.82 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL4437111 | 0.82 | SHBG (0.69) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11669558 | 0.74 | LMNA (0.43) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL3173361 | 0.74 | PDK1 (0.70) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11855930 | 0.74 | SHBG (0.66) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL3444251 | 0.74 | PDK1 (0.70) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11864812 | 0.73 | SERPINA6 (0.41) | SHBGSERPINA6SLC22A1ALDH1A1THRB | |
| SCHEMBL11868449 | 0.73 | SHBG (0.65) | SHBGSERPINA6SLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959322-A | Synthesis of 13-alkyl-gon-4-ones | Smith, Herchel (US) | 1976-05-25 | — | — | US | disclosed |