SCHEMBL116696

SCHEMBL116696

Clc1nc2ccccc2nc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 1.00
MAPT P10636 4/20 0.62
KDM4E B2RXH2 5/20 0.61
PKM P14618 1/20 0.61
L3MBTL1 Q9Y468 4/20 0.52
ALDH1A1 P00352 3/20 0.50
GAA P10253 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
KMT2A Q03164 3/20 0.48
NQO2 P16083 2/20 0.48
HTR3B O95264 1/20 0.47
HTR3A P46098 1/20 0.47
HRH4 Q9H3N8 1/20 0.47
LMNA P02545 1/20 0.46
NPSR1 Q6W5P4 2/20 0.45
RXFP1 Q9HBX9 1/20 0.45
PDE4A P27815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29451077 1.00 TDP1 (1.00) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL11206926 0.87 TDP1 (0.75) TDP1MAPTKDM4EPKML3MBTL1
Bicarbonate SCHEMBL10870596 0.87 TDP1 (0.75) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL9157834 0.84 TDP1 (0.71) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL10908621 0.83 TDP1 (0.68) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL1670942 0.81 TDP1 (0.67) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL874110 0.81 TDP1 (0.67) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL2877056 0.81 TDP1 (0.67) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL3085978 0.81 TDP1 (0.67) TDP1MAPTKDM4EPKML3MBTL1
SCHEMBL121118 0.81 MAPT (0.67) TDP1MAPTKDM4EPKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2306 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521341-B2 Injectable compositions BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-01-13 US claimed
EP-3711743-B1 CATIONIC CELLULOSE AND COMPOSITION FOR TREATING HAIR, SKIN, OR FIBER INCLUDING SAME LG HOUSEHOLD & HEALTH CARE LTD (KR) 2025-07-23 EP claimed
CN-119433974-A Preparation method of crosslinked cellulose fiber 中国纺织科学研究院有限公司 2025-02-14 CN claimed
CN-115960044-B Treatment method of copper quinolinate mother liquor 泰安汉威集团有限公司 2024-06-25 CN claimed
US-20240139097-A1 INJECTABLE COMPOSITIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-05-02 US claimed
CN-117820318-A P-type organic positive electrode material and preparation method and application thereof 上海电力大学 2024-04-05 CN claimed
US-11938216-B2 Injectable compositions BOSTON SCIENTIFIC SCIMED, INC. (US) 2024-03-26 US claimed
US-11649232-B2 Synthetic dimeric cinchona alkaloids against cancer Ares Pharmaceuticals, LLC (US) 2023-05-16 US claimed
CN-115911370-A Novel negative electrode material for water-based battery, water-based battery and preparation method of water-based battery 广西电网有限责任公司电力科学研究院 2023-04-04 CN claimed
CN-115636797-A Method for preparing 5,6-dichloro-2,3-pyrazine diacid 台州国赐医药技术有限公司 2023-01-24 CN claimed
EP-0076986-A1 Process for dyeing or/and printing mercerized or causticized natural or regenerated cellulose Dollfus-Mieg & Cie. D.M.C. (FR) 1983-04-20 EP claimed
WO-1983001261-A1 METHOD FOR DYEING AND/OR PRINTING OF NATURAL OR REGENERATED MERCERIZED OR CAUSTICIZED CELLULOSE MADOUX, ALAN 1983-04-14 WO claimed
EP-0069300-A1 Liquid preparations of reactive dyes and their use HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-12 EP claimed
EP-0041239-A2 Stable concentrated liquid preparations of non metalliferous dyes, their preparation process and their use CIBA-GEIGY AG (CH) 1981-12-09 EP claimed
US-4285694-A Cold padding batch dyeing process for tubular knitted fabrics NITTOBO ITAMIKAKO CO., LTD. (JP) 1981-08-25 US claimed
US-4215988-A HYDROXYMETHANE-SULFONIC ACID SALT AS DYE RESIST FOR VINYL SULFONE TYPE REACTIVE DYES MEISEI CHEMICAL WORKS, LTD. (JP) 1980-08-05 US claimed
US-4138551-A DINUCLEAR CYANINE OR MEROCYANINE DYE REACTIVE WITH HYDROPHILIC COLLODI CIBA-GEIGY AG (CH) 1979-02-06 US claimed
US-4134724-A Process for dyeing highly moisture absorbent cellulose containing textile materials MILLIKEN RESEARCH CORPORATION (US) 1979-01-16 US claimed
US-4119460-A FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS EASTMAN KODAK COMPANY (US) 1978-10-10 US claimed
US-4025510-A DYES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-24 US claimed