SCHEMBL9157834

SCHEMBL9157834

Clc1nc2ccccc2nc1Cl.O=C(O)Cl

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
ALDH1A1 P00352 5/20 0.54
SMN1; SMN2 Q16637 4/20 0.54
MAPT P10636 2/20 0.54
KDM4E B2RXH2 5/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 2/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
NPSR1 Q6W5P4 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
GAA P10253 2/20 0.42
MGAM O43451 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL10870596 0.93 TDP1 (0.75) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL11206926 0.93 TDP1 (0.75) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL116696 0.84 TDP1 (1.00) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL29451077 0.84 TDP1 (1.00) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL6992814 0.80 TDP1 (0.56) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL634399 0.80 ALDH1A1 (0.72) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL10908621 0.79 TDP1 (0.68) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
Hydrochloric Acid SCHEMBL10562751 0.79 ALDH1A1 (0.69) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
Phenazine SCHEMBL6213173 0.76 MAPT (0.69) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E
SCHEMBL3701892 0.76 TDP1 (0.56) TDP1ALDH1A1SMN1; SMN2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023955-B1 PROCESS OF PREPARATION OF COPPER COMPLEXES OF DISAZO-DYESTUFFS BAYER AG (DE) 1983-09-21 EP claimed
EP-0465829-B1 Reactive azodyes BAYER AG (DE) 1995-01-11 EP disclosed
EP-0465829-A1 Reactive azodyes BAYER AG (DE) 1992-01-15 EP disclosed
EP-0167952-B1 DYE SOLUTIONS BAYER AG (DE) 1991-07-24 EP disclosed
EP-0167952-A2 Dye solutions BAYER AG (DE) 1986-01-15 EP disclosed
EP-0043927-B1 PROCESS FOR PREPARING REACTIVE AZO DYESTUFFS BAYER AG (DE) 1984-05-16 EP disclosed
EP-0023955-B1 PROCESS OF PREPARATION OF COPPER COMPLEXES OF DISAZO-DYESTUFFS BAYER AG (DE) 1983-09-21 EP disclosed
EP-0043927-A2 Process for preparing reactive azo dyestuffs BAYER AG (DE) 1982-01-20 EP disclosed
EP-0001451-B1 WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1981-09-23 EP disclosed
EP-0023955-A1 Process of preparation of copper complexes of disazo-dyestuffs BAYER AG (DE) 1981-02-18 EP disclosed
EP-0001451-A1 Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1979-04-18 EP disclosed