Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116696 | 0.81 | TDP1 (1.00) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL29364974 | 0.81 | MAPT (0.62) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL29451077 | 0.81 | TDP1 (1.00) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL103601 | 0.81 | MAPT (0.62) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL12597038 | 0.79 | PIK3R1 (0.46) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL11011451 | 0.78 | MAPT (0.59) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| Water SCHEMBL27864881 | 0.78 | MAPT (0.59) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL27821564 | 0.78 | MAPT (0.59) | TDP1L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL6311061 | 0.78 | KMT2A (0.62) | TDP1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL14764426 | 0.78 | NQO2 (0.57) | TDP1L3MBTL1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4119460-A | FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1978-10-10 | — | — | US | claimed |
| US-20260102762-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2026-04-16 | — | — | US | disclosed |
| US-12539508-B2 | Tri-(adamantyl) phosphines and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2026-02-03 | — | — | US | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| US-20240336591-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2024-10-10 | — | — | US | disclosed |
| EP-4377305-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | BenevolentAI Cambridge Limited (GB) | 2024-06-05 | — | — | EP | disclosed |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-04 | — | — | US | disclosed |
| CN-117751107-A | Organic pyridine-pyrazole compounds and uses thereof | 博善人工智能剑桥有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-20240001353-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | UNIV PRINCETON (US) | 2024-01-04 | — | — | US | disclosed |
| EP-4286051-A2 | A METHOD OF CROSS-COUPLING USING A TRANSITION METAL COMPLEX COMPRISING A PAD3 LIGAND | The Trustees of Princeton University (US) | 2023-12-06 | — | — | EP | disclosed |
| US-4609396-A | GRASSES IN BROADLEAF CROPS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| US-4608383-A | Cardioactive pyrazole and imidazole aryloxypropanolamines | BOEHRINGER MANNHEIM GMBH (DE) | 1986-08-26 | — | — | US | disclosed |
| EP-0042593-B1 | ARYLOXY-PROPANOL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1985-04-03 | — | — | EP | disclosed |
| US-4438128-A | ADRENERGIC BLOCKERS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-03-20 | — | — | US | disclosed |
| US-4349674-A | Quinoalinyl esters of carbamimidothioic acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| US-4330461-A | FIREPROOFING POLYESTERS AND POLYAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-05-18 | — | — | US | disclosed |
| EP-0042750-A2 | Quinoxalinyloxy ethers as selective weed control agents | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
| EP-0042593-A1 | Aryloxy-propanol amines, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | disclosed |
| US-4234729-A | FIREPROOFING POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-11-18 | — | — | US | disclosed |
| US-4119460-A | FUSED CARBOCYCLIC RING COMPOUNDS, POLYPHENYL COMPOUNDS NITROGEN-FREE POLYARYLATED COMPOUNDS | EASTMAN KODAK COMPANY (US) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12539508-B2 | Tri-(adamantyl) phosphines and applications thereof | OTC, AOC3, ICOSLG | TDP1 571/4885L3MBTL1 4232/4885KDM4E 2247/4885 |
| US-20260102762-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | PTMS, TEC, CD2 | TDP1 425/4885L3MBTL1 4551/4885KDM4E 2155/4885 |
| US-20240001353-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | PADI3, ADA, ENTPD3 | TDP1 116/4885L3MBTL1 4016/4885KDM4E 1696/4885 |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | HCRTR2, HCRTR1, OXTR | TDP1 3692/4885L3MBTL1 4510/4885KDM4E 454/4885 |
| US-20240336591-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | ALPI, NOD1, PNPO | TDP1 2304/4885L3MBTL1 4868/4885KDM4E 3633/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | TDP1 3692/4885L3MBTL1 4510/4885KDM4E 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.