Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422374 | 0.92 | ALDH1A1 (0.65) | ALDH1A1HPGDSMN1; SMN2HTTDRD2 | |
| SCHEMBL3445006 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2DRD2DRD1 | |
| SCHEMBL2424933 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2HTTPTGDR2 | |
| SCHEMBL31528226 | 0.83 | ALDH1A1 (0.67) | ALDH1A1HPGDSMN1; SMN2HTTPTGDR2 | |
| SCHEMBL1283679 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4ETDP1MAOBKMT2A | |
| SCHEMBL3283885 | 0.81 | FLT3 (0.61) | ALDH1A1HPGDSMN1; SMN2HTTDRD2 | |
| SCHEMBL195416 | 0.81 | ALDH1A1 (0.74) | ALDH1A1HPGDSMN1; SMN2HTTPTGDR2 | |
| SCHEMBL11735898 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDSMN1; SMN2HTTDRD2 | |
| SCHEMBL8372730 | 0.80 | ALDH1A1 (0.87) | ALDH1A1HPGDSMN1; SMN2HTTPTGDR2 | |
| SCHEMBL5805320 | 0.80 | ALDH1A1 (0.87) | ALDH1A1HPGDSMN1; SMN2HTTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-03-14 | — | — | CN | disclosed |
| US-4064125-A | Substituted amides having antiinflammatory activity | E. R. SQUIBB AND SONS, INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-3968117-A | CARDIOVASCULAR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-06 | — | — | US | disclosed |
| US-3959296-A | CARDIOVASCULAR AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |