SCHEMBL3445006

SCHEMBL3445006

C=Cc1ccccc1OCCCN(CC)CC

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
HTR1B P28222 2/20 0.47
HTR1D P28221 1/20 0.47
KDM4E B2RXH2 4/20 0.47
TDP1 Q9NUW8 1/20 0.47
DRD2 P14416 1/20 0.47
DRD1 P21728 1/20 0.47
DRD3 P35462 1/20 0.47
BIRC5 O15392 1/20 0.44
LMNA P02545 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
MAOB P27338 1/20 0.43
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FLT3 P36888 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3445434 0.95 ALDH1A1 (0.63) ALDH1A1HTR1BHTR1DKDM4ETDP1
SCHEMBL3445440 0.94 ALDH1A1 (0.66) ALDH1A1HTR1BHTR1DDRD2DRD1
SCHEMBL3445531 0.94 ALDH1A1 (0.66) ALDH1A1HTR1BHTR1DDRD2DRD1
SCHEMBL3444957 0.89 HTR1B (0.55) ALDH1A1HTR1BHTR1DKDM4EBCHE
SCHEMBL3445823 0.89 HTR1B (0.48) ALDH1A1HTR1BHTR1DKDM4EBCHE
SCHEMBL3445323 0.86 HTR1B (0.52) ALDH1A1HTR1BHTR1DKDM4EBCHE
SCHEMBL3445405 0.86 LMNA (0.44) ALDH1A1HTR1BHTR1DLMNAHPGD
SCHEMBL3445043 0.84 HTR1B (0.54) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL3446798 0.84 ALDH1A1 (0.50) ALDH1A1HTR1BHTR1DBCHEACHE
SCHEMBL11669697 0.84 ALDH1A1 (0.62) ALDH1A1HTR1BHTR1DKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed