SCHEMBL2424933

SCHEMBL2424933

CN(C)CCCOc1ccccc1C=O

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
HPGD P15428 1/20 0.67
HTT P42858 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HRH1 P35367 2/20 0.58
HTR1B P28222 2/20 0.57
PTGDR2 Q9Y5Y4 1/20 0.51
KDM4E B2RXH2 3/20 0.50
ADRB2 P07550 1/20 0.49
ADRB1 P08588 1/20 0.49
HTR7 P34969 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31528226 1.00 ALDH1A1 (0.67) ALDH1A1HPGDHTTSMN1; SMN2HRH1
SCHEMBL11729416 0.95 ALDH1A1 (0.65) ALDH1A1HPGDHTTSMN1; SMN2HRH1
SCHEMBL19328405 0.93 ALDH1A1 (0.62) ALDH1A1HPGDHTTSMN1; SMN2HRH1
SCHEMBL4888000 0.91 ALDH1A1 (0.69) ALDH1A1HPGDHTTSMN1; SMN2HRH1
Hydrochloric Acid SCHEMBL6561435 0.90 ALDH1A1 (0.67) ALDH1A1HPGDHTTSMN1; SMN2HRH1
SCHEMBL11669697 0.83 ALDH1A1 (0.62) ALDH1A1HPGDHTTSMN1; SMN2HTR1B
SCHEMBL5805320 0.83 ALDH1A1 (0.87) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL8372730 0.83 ALDH1A1 (0.87) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2
SCHEMBL3446273 0.83 HTR1B (0.57) ALDH1A1HRH1HTR1BKDM4EHTR7
SCHEMBL19342150 0.82 ALDH1A1 (0.66) ALDH1A1HPGDHTTSMN1; SMN2PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2245132-B1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC NO 41424 (GB) 2017-10-18 EP claimed
EP-2245132-A1 ENCAPSULATED BENEFIT AGENT Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) 2010-11-03 EP claimed
WO-2009103576-A1 ENCAPSULATED BENEFIT AGENT UNILEVER PLC (GB) 2009-08-27 WO claimed
US-12281119-B2 Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist BEIGENE, LTD. (KY) 2025-04-22 US disclosed
EP-3921320-B1 IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEIGENE LTD (KY) 2024-03-06 EP disclosed
US-20220119394-A1 IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEONE MEDICINES I GMBH (CH) 2022-04-21 US disclosed
US-20210070756-A1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2021-03-11 US disclosed
US-20200291027-A1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2020-09-17 US disclosed
EP-3539962-A1 TETRACYCLIC BROMODOMAIN INHIBITORS AbbVie Inc. (US) 2019-09-18 EP disclosed
EP-2970330-B1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2019-04-17 EP disclosed
US-20180298003-A1 TETRACYCLIC BROMODOMAIN INHIBITORS ABBVIE INC (US) 2018-10-18 US disclosed
US-4127606-A Substituted sulfonamides having antiinflammatory activity E. R. SQUIBB & SONS, INC. (US) 1978-11-28 US disclosed
US-4122255-A Substituted amides and sulfonamides containing a heterocyclic group having antiinflammatory activity E. R. SQUIBB & SONS, INC. (US) 1978-10-24 US disclosed
US-4098789-A ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1978-07-04 US disclosed
US-4064120-A 3,3-Dichloro-2-azetidinone derivatives having antiinflammatory activity E. R. SQUIBB & SONS, INC. (US) 1977-12-20 US disclosed
US-4064125-A Substituted amides having antiinflammatory activity E. R. SQUIBB AND SONS, INC. (US) 1977-12-20 US disclosed
US-4053471-A ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1977-10-11 US disclosed
US-4053514-A ANTIDEPRESSANTS E. R. SQUIBB & SONS, INC. (US) 1977-10-11 US disclosed
US-4038274-A ANTIDEPRESSANTS E. R. SQUIBB & SONS, INC. (US) 1977-07-26 US disclosed
US-3969527-A INDENO(1,2-C)PYRAZOLE E. R. SQUIBB & SONS, INC. (US) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180298003-A1 TETRACYCLIC BROMODOMAIN INHIBITORS BRD3, BRD4, BRD1 ALDH1A1 2163/4885HPGD 2388/4885HTT 1423/4885
US-20200291027-A1 TETRACYCLIC BROMODOMAIN INHIBITORS BRD3, BRD4, BRD1 ALDH1A1 2163/4885HPGD 2388/4885HTT 1423/4885
US-20210070756-A1 TETRACYCLIC BROMODOMAIN INHIBITORS BRD3, BRD4, BRD1 ALDH1A1 2163/4885HPGD 2388/4885HTT 1423/4885
US-20220119394-A1 IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST TLR7, TLR1, TLR3 ALDH1A1 1611/4885HPGD 4530/4885HTT 4372/4885
US-12281119-B2 Imidazo[2,1-f][1,2,4]triazin-4-amine derivatives as TLR7 agonist TLR7, TLR1, TLR3 ALDH1A1 1611/4885HPGD 4530/4885HTT 4372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.