Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 5/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15935985 | 0.87 | ACP1 (0.40) | KMT2ASTAT3ACP1PTPN12PTPN13 | |
| SCHEMBL10463996 | 0.82 | MEN1 (0.43) | KMT2AMEN1CCR5 | |
| SCHEMBL31398241 | 0.81 | KMT2A (0.45) | KMT2AMEN1 | |
| SCHEMBL3978402 | 0.79 | ADRA1D (0.45) | KMT2AMEN1LMNAHTT | |
| SCHEMBL11670459 | 0.79 | MEN1 (0.38) | KMT2AMEN1SLC1A5CCR5 | |
| SCHEMBL6074837 | 0.78 | ADRB3 (0.50) | — | |
| SCHEMBL11748916 | 0.77 | ELANE (0.40) | KMT2AMEN1 | |
| SCHEMBL11670137 | 0.77 | MEN1 (0.38) | KMT2AMEN1STAT3ACP1PTPN12 | |
| SCHEMBL11670700 | 0.75 | NR1H3 (0.40) | KMT2AMEN1 | |
| SCHEMBL3978396 | 0.75 | ADRB2 (0.43) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328512-A2 | CYCLYLAMINE SULFONAMIDES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002006221-A2 | CYCLYLAMINE SULFONAMIDES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |