Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28141466 | 0.86 | TP53 (0.52) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL3234327 | 0.85 | CES2 (0.68) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL8720245 | 0.85 | TP53 (0.58) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL181572 | 0.85 | CES2 (0.78) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL8962651 | 0.84 | CES2 (0.66) | TSHRCES2CES1MEN1KMT2A | |
| Hydrazine SCHEMBL27600958 | 0.84 | TP53 (0.69) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL8962645 | 0.84 | CES2 (0.66) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL333455 | 0.84 | TP53 (0.73) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL8962468 | 0.84 | CES2 (0.75) | TSHRCES2CES1MEN1KMT2A | |
| SCHEMBL11758821 | 0.83 | TP53 (0.77) | TSHRCES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035350-A | Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |