Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670232 | 0.85 | TSHR (0.59) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL333455 | 0.85 | TP53 (0.73) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL8720282 | 0.84 | MEN1 (0.58) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL11758821 | 0.83 | TP53 (0.77) | TP53CES2CES1MEN1KMT2A | |
| Phosphine SCHEMBL28281304 | 0.83 | TP53 (0.71) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL3234327 | 0.83 | CES2 (0.68) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL11295596 | 0.83 | TP53 (0.71) | TP53CES2CES1MEN1KMT2A | |
| SCHEMBL27787065 | 0.83 | TP53 (0.71) | TP53CES2CES1MEN1KMT2A | |
| Bicarbonate SCHEMBL27282989 | 0.83 | TP53 (0.71) | TP53CES2CES1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL27493385 | 0.83 | TP53 (0.71) | TP53CES2CES1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045298-A1 | ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |