Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670878 | 0.96 | KMT2A (0.40) | LMNAS1PR1ALDH1A1POLBKMT2A | |
| SCHEMBL11670883 | 0.93 | GHSR (0.41) | S1PR1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL11672067 | 0.92 | S1PR1 (0.41) | S1PR1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL11671693 | 0.92 | LMNA (0.46) | LMNAALDH1A1KMT2AMAPTGAA | |
| SCHEMBL11672314 | 0.90 | S1PR1 (0.41) | S1PR1ALDH1A1KMT2AMAPTNPC1 | |
| SCHEMBL11671280 | 0.90 | S1PR1 (0.42) | S1PR1ALDH1A1MAPTNPC1GAA | |
| SCHEMBL11671594 | 0.89 | LMNA (0.44) | LMNAALDH1A1KMT2AMAPTGAA | |
| SCHEMBL11670567 | 0.88 | MTNR1B (0.44) | LMNAALDH1A1KMT2AMAPTGAA | |
| SCHEMBL11670409 | 0.88 | LMNA (0.40) | LMNAALDH1A1POLBKMT2AMAPT | |
| SCHEMBL11670757 | 0.87 | GHSR (0.41) | ALDH1A1MAPTKDM4EGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |