Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789579 | 0.78 | CES2 (0.38) | TSHR | |
| SCHEMBL8788775 | 0.78 | CES2 (0.38) | TSHR | |
| SCHEMBL2142264 | 0.78 | CES2 (0.38) | TSHR | |
| SCHEMBL11956974 | 0.74 | — | — | |
| SCHEMBL8698845 | 0.74 | SLC2A1 (0.32) | — | |
| SCHEMBL8702420 | 0.74 | SLC2A1 (0.32) | — | |
| SCHEMBL172020 | 0.71 | CES2 (0.32) | — | |
| SCHEMBL25974005 | 0.71 | NOS2 (0.33) | MGLL | |
| SCHEMBL3075371 | 0.71 | CES2 (0.41) | TSHRGAACA1CA2MGLL | |
| SCHEMBL3074321 | 0.71 | MGLL (0.42) | GAACA1CA2MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059699-A | O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites | GULF OIL CORPORATION (US) | 1977-11-22 | — | — | US | claimed |
| US-3994997-A | MITICIDES, INSECTICIDES | GULF OIL CORPORATION (US) | 1976-11-30 | — | — | US | claimed |
| US-4059699-A | O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites | GULF OIL CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-4059699-A | O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites | GULF OIL CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-3994997-A | MITICIDES, INSECTICIDES | GULF OIL CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3994997-A | MITICIDES, INSECTICIDES | GULF OIL CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |