Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 4/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672334 | 0.93 | ALDH1A1 (0.37) | VCAM1SMN1; SMN2MCOLN3LMNAALDH1A1 | |
| SCHEMBL11670279 | 0.88 | SMN1; SMN2 (0.39) | VCAM1SMN1; SMN2POLBMCOLN3LMNA | |
| SCHEMBL11510273 | 0.84 | VCAM1 (0.42) | VCAM1SMN1; SMN2POLBMCOLN3LMNA | |
| SCHEMBL11670893 | 0.83 | TSHR (0.36) | ALDH1A1HTTMAPTTSHRKMT2A | |
| SCHEMBL11508081 | 0.76 | ALDH1A1 (0.43) | VCAM1SMN1; SMN2MCOLN3ALDH1A1NPSR1 | |
| SCHEMBL11670822 | 0.72 | VCAM1 (0.45) | VCAM1SMN1; SMN2POLBMCOLN3LMNA | |
| SCHEMBL11509567 | 0.71 | MCOLN3 (0.44) | VCAM1SMN1; SMN2MCOLN3LMNAALDH1A1 | |
| SCHEMBL10687962 | 0.66 | ALDH1A1 (0.47) | VCAM1SMN1; SMN2POLBMCOLN3LMNA | |
| SCHEMBL11510397 | 0.65 | ALDH1A1 (0.42) | VCAM1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL11671776 | 0.64 | ALDH1A1 (0.46) | VCAM1SMN1; SMN2MCOLN3ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041073-A | 3,4,5-Trichloro-N,N-di(loweralkyl)-2-(mercapto) benzenesulfonamides | THE DOW CHEMICAL COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-4035407-A | 3,4,5-Trichloro-N,N-di(loweralkyl)-2-thiomethylthiocyanato)benzene-sulfonamides | THE DOW CHEMICAL COMPANY (US) | 1977-07-12 | — | — | US | disclosed |